Photodynamic therapy of cervical intraepithelial neoplasia
| Autor: | Natalia Mayumi Inada, Vanderlei Salvador Bagnato, Cristina Kurachi, Jose Roberto Trujillo, Welington Lombardi, Marieli Fernanda Martins Leite |
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| Rok vydání: | 2014 |
| Předmět: |
Surgical resection
Cervical cancer medicine.medical_specialty business.industry medicine.medical_treatment Photodynamic therapy Cervical intraepithelial neoplasia medicine.disease medicine.anatomical_structure Methyl aminolevulinate medicine Photosensitizer Radiology Human papillomavirus business Cervix medicine.drug |
| Zdroj: | SPIE Proceedings. |
| ISSN: | 0277-786X |
| DOI: | 10.1117/12.2040004 |
| Popis: | Photodynamic therapy (PDT) is a technique that has been used for the treatment of tumors, especially in Gynecology. The photodynamic reaction is based on the production of reactive oxygen species after the activation of a photosensitizer. Advantages of the PDT in comparison to the surgical resection are: ambulatory treatment and tissue recovery highly satisfactory, through a non-invasive procedure. The cervical intraepithelial neoplasia (CIN) grades I and II presents potential indications for PDT. The aim of the proposed study is to evaluate the safety and efficacy of the PDT for the diagnostics and treatment of CIN I and II. The equipment and the photosensitizer are produced in Brazil with a representative low cost. It is possible to visualize the fluorescence of the cervix and to treat the lesions, without side effects. The proposed clinical protocol shows great potential to become a public health technique. |
| Databáze: | OpenAIRE |
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