Wernicke-Korsakoff Syndrome: A Common Yet Elusive Diagnosis

Autor:	Tiago Santos, Nuno Madeira, J.L. Pio-Abreu
Rok vydání:	2009
Předmět:	Psychiatry and Mental health medicine.medical_specialty Wernicke–Korsakoff syndrome Encephalopathy Epidemiology medicine Alcohol abuse Thiamine Differential diagnosis Cognitive impairment Psychiatry medicine.disease Psychology
Zdroj:	European Psychiatry. 24:1-1
ISSN:	1778-3585 0924-9338
DOI:	10.1016/s0924-9338(09)71095-8
Popis:	In 1897, Murawieff proposed that a common cause was responsible for the two syndromes previously described by Carl Wernicke and Sergei Korsakoff. More than 100 years afterwards, the neuropsychiatric nosological entity known as Wernicke-Korsakoff syndrome remains one of the most significant, yet under-recognized, consequences of long-term alcohol abuse.Prompt recognition and treatment of Wernicke's encephalopathy with parenteral thiamine can prevent permanent cognitive impairment, involving severe short-term memory loss - Korsakoff's amnesic syndrome. Such condition has devastating consequences for patients, not infrequently demanding long-term institutionalization.Based on two clinical vignettes, the authors review some epidemiological, clinical and neuropathological features of Wernicke-Korsakoff syndrome, besides issues concerning differential diagnosis, treatment and prognosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cf765108db1668efd8e7135e60ddb814 https://doi.org/10.1016/s0924-9338(09)71095-8 Zobrazit plný text záznamu