In vitro display evolution of unnatural peptides spontaneously cyclized via intramolecular nucleophilic aromatic substitutions
Autor: | Takumi Yokoyama, Takehiro Ando, Yukio Takamori, Daisuke Fuji, Masashi Sato, Santhana Vedi, Mizuki Yamamoto, Takashi Kawakami |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Chemical Communications. 58:5237-5240 |
ISSN: | 1364-548X 1359-7345 |
DOI: | 10.1039/d2cc00584k |
Popis: | We report novel spontaneous peptide cyclization by intramolecular nucleophilic aromatic substitutions using ribosomally incorporatable and intramolecularly cysteine-reactive fluorobenzoic acid-derived linkers. |
Databáze: | OpenAIRE |
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