In vitro display evolution of unnatural peptides spontaneously cyclized via intramolecular nucleophilic aromatic substitutions

Autor: Takumi Yokoyama, Takehiro Ando, Yukio Takamori, Daisuke Fuji, Masashi Sato, Santhana Vedi, Mizuki Yamamoto, Takashi Kawakami
Rok vydání: 2022
Předmět:
Zdroj: Chemical Communications. 58:5237-5240
ISSN: 1364-548X
1359-7345
DOI: 10.1039/d2cc00584k
Popis: We report novel spontaneous peptide cyclization by intramolecular nucleophilic aromatic substitutions using ribosomally incorporatable and intramolecularly cysteine-reactive fluorobenzoic acid-derived linkers.
Databáze: OpenAIRE