Seltene und spezielle Indikationen für eine nuklearmedizinische Entzündungsdiagnostik
| Autor: | A. Hamann, C. O. Sahlmann, S. Tesche, Birgit Meller, Johannes Meller, U. Siefker |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Fluorodeoxyglucose
Pathology medicine.medical_specialty medicine.diagnostic_test business.industry medicine.drug_class medicine.disease Scintigraphy Monoclonal antibody Inflammatory bowel disease Appendicitis 3. Good health Isotopes of technetium Monoclonal medicine Endocarditis business medicine.drug |
| Zdroj: | Der Nuklearmediziner. 30:154-167 |
| ISSN: | 1439-5800 0723-7065 |
| DOI: | 10.1055/s-2007-960530 |
| Popis: | This article gives an evidence-based overview about several special indications for scintigraphy in imaging infection and inflammation. In diagnosing and evaluating the extent of inflammatory bowel disease, the scintigraphy with 99m Tc-HMPAO labelled leucocytes remains the standard evaluation in Nuclear Medicine. Appendicitis can be proven or excluded with a high grade of certainty both by 99m Tc-labelled monoclonal antigranulocytic antibodies and FAb′-fragments and by in-vitro labelled leucocytes. In endocarditis a late SPECT (20-24 h p. i.) with a 99m Tc-labeled anti-CD66 monoclonal antibody is a useful adjunct to echocardiographic techniques. In infected vascular prostheses, 99m Tc-HMPAO-labelled autologous leucocytes remain the standard of Nuclear Medicine although [ 18 F]FDG-PET or [ 18 F]FDG-PET / CT may exhibit a higher diagnostic accuracy. |
| Databáze: | OpenAIRE |
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