| Autor: |
Salman Shams, Razia Bano, Madiha Shah, Ali Raza Memon, Ali Akber Nangraj, Sarwat Ashraf, Asif Aziz |
| Rok vydání: |
2022 |
| Zdroj: |
Journal of Pharmaceutical Research International. :43-48 |
| ISSN: |
2456-9119 |
| DOI: |
10.9734/jpri/2022/v34i20a35825 |
| Popis: |
Background: Hypertension is one of the leading cause of morbidity and mortality in all over the world as in developed and under developing countries. Hypertension mostly associated with other clinical chronic disorders like diabetes mellitus, hyperuricemia, dyslipidemia etc. The ACE inhibitors are a kind of antihypertensive drug that is widely using all over the world. ACE inhibitors lowers blood pressure, but also lower uric acid levels as well. Aims & Objectives: To evaluate the efficacy of ACE inhibitors alone and along with the folic acid on systolic & diastolic blood pressure & on serum uric acid level. Methodology: This case-control research was carried out at the Medicine Department with the help of the Department of Biochemistry at LUMHS Jamshoro and the PAQSJ Medical Institute in Gambat. A total of 200 mild to moderate hypertension individuals with hyperuricemia were chosen. They were divided into two groups: the control group was taken 10 mg of lisinopril, while the case study group received 10 mg of lisinopril with 0.8 mg of folic acid for 10 to 12 weeks. Results: The mean value of systolic B.P in control group after treatment was126 ± 4.9 (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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