NCCN Guidelines Insights: Primary Cutaneous Lymphomas, Version 2.2020

Autor: Deepa Jagadeesh, Joan Guitart, Gaurav Goyal, Ahmad Halwani, Eric D. Jacobsen, Richard T. Hoppe, Jasmine Zain, Mary A. Dwyer, Aaron C. Shaver, Jeffrey A. Barnes, Ryan A. Wilcox, Steven M. Horwitz, Ahmet Dogan, Mark W. Clemens, Basem M. William, Elise A. Olsen, Youn H. Kim, Amitkumar Mehta, Stephen M. Ansell, Bradley M. Haverkos, Andrei R. Shustov, Lubomir Sokol, Barbara Pro, Stefan K. Barta, Carlos A. Torres-Cabala, Neha Mehta-Shah, Satish Shanbhag, Weiyun Z. Ai, Pallawi Torka, Hema Sundar, Matthew A. Lunning, Saurabh Rajguru, Aaron M. Goodman, Kristopher R. Fisher
Rok vydání: 2020
Předmět:
Zdroj: Journal of the National Comprehensive Cancer Network. 18:522-536
ISSN: 1540-1413
1540-1405
DOI: 10.6004/jnccn.2020.0022
Popis: Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma (CTCL), and Sézary syndrome (SS) is a rare erythrodermic and leukemic subtype of CTCL characterized by significant blood involvement. Although early-stage disease can be effectively treated predominantly with skin-directed therapies, systemic therapy is often necessary for the treatment of advanced-stage disease. Systemic therapy options have evolved in recent years with the approval of novel agents such as romidepsin, brentuximab vedotin, and mogamulizumab. These NCCN Guidelines Insights discuss the diagnosis and management of MF and SS (with a focus on systemic therapy).
Databáze: OpenAIRE