Autor: | Jeffry G. Weers, Catherine M. Woods, Simona Bot, Shelly Harders, Dan Smith, Adrian Bot, William J Phillips, Luis A. Dellamary, Thomas E. Tarara |
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Rok vydání: | 2001 |
Předmět: |
Pharmacology
biology Organic Chemistry Orthomyxoviridae Antigen presentation Pharmaceutical Science Receptor-mediated endocytosis biology.organism_classification Virus Microbiology Immune system biology.protein Molecular Medicine Pharmacology (medical) Antibody Microparticle Drug carrier Biotechnology |
Zdroj: | Pharmaceutical Research. 18:971-979 |
ISSN: | 0724-8741 |
DOI: | 10.1023/a:1010988311640 |
Popis: | Purpose. Spray-dried lipid-based microparticles (SDLM) serve as a platform for delivery of a wide variety of compounds including peptides, proteins, and vaccines to the respiratory mucosa. In the present study, we assessed the impact of IgG-mediated targeting to phagocytic cells of inactivated influenza virus formulated in SDLM, on subsequent immune responses. |
Databáze: | OpenAIRE |
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