ANODIZED LAYERS ON TITANIUM AND TITANIUM ALLOY ORTHOPEDIC MATERIALS FOR ANTIMICROBIAL ACTIVITY APPLICATIONS
| Autor: | D. S. Dunn, Srini Raghavan, R. G. Volz |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Materials science
Anodizing Mechanical Engineering Oxide chemistry.chemical_element Titanium alloy Rutherford backscattering spectrometry Industrial and Manufacturing Engineering Streaming current chemistry.chemical_compound chemistry Mechanics of Materials General Materials Science Implant Composite material Porosity Titanium Biomedical engineering |
| Zdroj: | Materials and Manufacturing Processes. 7:123-137 |
| ISSN: | 1532-2475 1042-6914 |
| DOI: | 10.1080/10426919208947402 |
| Popis: | The development of a post operative infection following the implantation of a foreign material, such as a total joint prosthesis, is one of the most feared complications in orthopedic surgery. Prevention of such bacterial infections is best accomplished through the delivery of antibiotics as close to the implant as possible. A novel method has been developed to attach, retain and release antibiotics from titanium based materials. This technique consists of forming porous surface coatings by anodizing and using the surface chemical properties of the oxide coatings to attach antibiotics. Coatings with pores in the size range 0.1 to 10 urn have been formed in acid as well as basic solutions. The thickness, stoichiometry and morphology of the coatings have been characterized by Rutherford backscattering spectrometry and electron spectroscopy techniques. The isoelectric point of the coatings has been measured by a streaming potential technique. The attachment and retainment of gentamicin sulfate, a ca... |
| Databáze: | OpenAIRE |
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