Induction and transfer of resistance to poisoning byAmorimia (Mascagnia) septentrionalisin goats

Autor: Fabricio K. L. Carvalho, Valéria Medeiros de Mendonça Costa, James A. Pfister, Stephen T. Lee, Rosane M.T. Medeiros, Amélia Lizziane Leite Duarte, Franklin Riet-Correa, Daniel Cook
Rok vydání: 2013
Předmět:
Zdroj: Journal of Applied Toxicology. 34:220-223
ISSN: 0260-437X
DOI: 10.1002/jat.2860
Popis: Amorimia septentrionalis contains sodium monofluoroactetate (MFA) and can cause acute heart failure in ruminants when ingested in toxic doses. In this study, we demonstrate that resistance to poisoning by A. septentrionalis can be improved in goats by the repeated administration of non-toxic doses of A. septentrionalis. We also show that increased resistance to poisoning by A. septentrionalis can also be achieved by the transfaunation of ruminal content from goats previously conditioned to be resistant to naive goats. These methods of improving resistance require further study, but appear to provide potential management solutions to mitigate toxicity problems from A. septentrionalis, and perhaps other plant species containing MFA. Copyright © 2013 John Wiley & Sons, Ltd.
Databáze: OpenAIRE