The effect of dietary vitamin c and e supplementation on the toxicity of methyl oleate hydroperoxide (MOHP), a proposed toxic ozone intermediate

Autor:	M. Anne Stoddard, Janet Victor, Edward J. Calabrese
Rok vydání:	1985
Předmět:	Vitamin Antioxidant Vitamin C Chemistry medicine.medical_treatment Vitamin E Pharmacology Ascorbic acid Pollution Methemoglobin chemistry.chemical_compound Biochemistry Toxicity medicine Tocopherol
Zdroj:	Journal of Environmental Science and Health . Part A: Environmental Science and Engineering. 20:251-267
ISSN:	0360-1226
DOI:	10.1080/10934528509375224
Popis:	This study assessed the effects of vitamin E (600 mg/day) and/or vitamin C (one gram/day) supplementation for 4 weeks in adult human male volunteers on the in vitro erythrocyte toxicity of a proposed toxic ozone (O3) intermediate [i.e. methyl oleate hydroperoxide (MOHP)]. The results indicated that neither antioxidant vitamin provided significant (p > 0.05) protection against MOHP‐induced changes in methemoglobin (METHB) and reduced glutathione (GSH) over a wide range of MOHP concentrations.
Databáze:	OpenAIRE
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