Hospital and ICU Admission Risk Associated With Comorbidities Among Children With COVID-19 Ancestral Strains
| Autor: | Stephanie P. Ungar, Sadie Solomon, Anna Stachel, Gail F. Shust, Katharine N. Clouser, Sejal M. Bhavsar, Jennifer Lighter |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Clinical Pediatrics. :000992282211506 |
| ISSN: | 1938-2707 0009-9228 |
| Popis: | A large proportion of children have been affected by COVID-19; we evaluated the association between comorbidities and hospitalization/ICU (intensive care unit) admission among 4097 children under age 21 years with symptomatic COVID-19 (not just polymerase chain reaction [PCR]–positive or multisystem inflammatory syndrome in children associated with COVID-19 [MIS-C]) from 2 large health systems from March 2020 to September 2021. Significant comorbidities and demographic factors identified by univariable analysis were included in a multivariable logistic regression compared with children ages 6 to 11 without comorbidities. In all, 475 children (11.6%) were hospitalized, of whom 25.5% required ICU admission. Children under 1 year had high hospitalization risk, but low risk of ICU admission. Presence of at least 1 comorbidity was associated with hospitalization and ICU admission (odds ratio [OR] > 4). Asthma, obesity, chronic kidney disease, sickle cell disease, bone marrow transplantation, and neurologic disorders were associated with hospitalization (adjusted odds ratio [AOR] > 2). Malignancy, intellectual disability, and prematurity were associated with ICU admission (AOR > 4). Comorbidities are significantly associated with hospitalization/ICU admission among children with COVID-19. |
| Databáze: | OpenAIRE |
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