Efficacy of treatment of vulva cancer patients and analysis of their hormonal status

Autor:	Ekaterina Alekseevna Nerodo, Galina Andreevna Nerodo
Rok vydání:	2012
Předmět:	Oncology Cancer Research medicine.medical_specialty business.industry Cancer medicine.disease Treatment efficacy Vulva medicine.anatomical_structure Internal medicine medicine business Hormone
Zdroj:	Journal of Clinical Oncology. 30:e21127-e21127
ISSN:	1527-7755 0732-183X
Popis:	e21127 Background: hormonodependency of vulva is wellknown. This broughtusto study hormonal status of vulva cancer patients depending on treatment efficacy Methods: we present comparative analysis of hormonal status of vulva cancer patients in two groups: group 1 (50 patients) without relapse of the disease in 5-year period, and group 2 (35 patients) with relapse developed within the first year. Blood concentrations of testosterone, progesterone, follicle-stimulating hormone (FSH), luteinizing hormone were determined in all patients under study by means of radiometric methods. Estrone, estradiol, estriol with subsequent calculation of their sum were determined in daily urine by Brown method. Results: In the presence of effect (group 1) initial total amount of estrogens was twice as large than in its absence. In group 1 estradiol concentration exceeded the corresponding parameter of group 2 by three times(7.6±0.6 & 1,4±0.3,p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ced7bebd7c29c7da5c9bd87d0f58539e https://doi.org/10.1200/jco.2012.30.15_suppl.e21127 Zobrazit plný text záznamu