A Study in Rural Uganda of Heterosexual Transmission of Human Immunodeficiency Virus
| Autor: | Bailey Rc |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Gynecology
medicine.medical_specialty education.field_of_study Transmission (medicine) business.industry Population Human immunodeficiency virus (HIV) Developing country General Medicine medicine.disease_cause Heterosexual transmission Male circumcision medicine Justice (ethics) education business Viral load Demography |
| Zdroj: | New England Journal of Medicine. 343:364-365 |
| ISSN: | 1533-4406 0028-4793 |
| Popis: | Largely ignored in the report by Quinn et al. of their study of the heterosexual transmission of HIV-1 in Uganda is the finding that 40 of 137 uncircumcised men who were negative for HIV-1 seroconverted whereas 0 of 50 circumcised men seroconverted. This finding suggests that male circumcision is at least as protective against female-to-male transmission of HIV-1 as low viral load in the female partner. Yet the authors do not consider male circumcision among their list of possible strategies for the prevention of HIV-1 infection. There are now more than 30 epidemiologic studies from sub-Saharan Africa dating back to 1987 that report a significant protective effect of male circumcision against HIV-1 infection. Is it not time for those in Rakai Uganda (where Quinn et al. conducted their study) as well as others to benefit from these studies? The feasibility of offering information on voluntary male circumcision and circumcision services to this community with a high prevalence of HIV-1 infection could at least be investigated. Justice and scientific evidence demand it. (full text) |
| Databáze: | OpenAIRE |
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