EnRAGEd: Introductory notes on aggression in a case of orbitofrontal syndrome

Autor: Jose Fernando Muñoz Zúñiga
Rok vydání: 2017
Předmět:
Zdroj: Neuropsychoanalysis. 19:77-86
ISSN: 2044-3978
1529-4145
DOI: 10.1080/15294145.2017.1295816
Popis: The orbitofrontal syndrome (OBS) is a neuropsychiatric syndrome secondary to damage in orbital areas of the prefrontal cortex. It is composed of cognitive, behavioral and affective symptoms of different grades of severity, often leading to permanent changes in personality. The case of a man who developed reactive, ego-dystonic, non-reflective and explosive aggression as part of an OBS secondary to a ruptured aneurism is examined. The clinical material is taken from multiple hospitalizations in a psychiatric clinic in Colombia, and from supportive therapy. A series of preliminary correlations are made between neuropsychiatric symptoms, neuropsychological data, neuroanatomical lesions as shown on neuroimaging and first-person subjective data. Using an affective neuroscience framework, it is hypothesized that damage to executive control of the RAGE system leads to altered functioning of neural hierarchies involved in affective processing, with affective attacks being experienced by the patient at a metapsych...
Databáze: OpenAIRE