Effects of telmisartan on serum adiponectin and left ventricular remodeling in patients with essential hypertension
| Autor: | Chun Gui Zheng, Shu Po Lin, Yong Tang Shi, Xiao Peng Tian, Qing Min Wei |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty animal structures Adiponectin business.industry Diastole 030204 cardiovascular system & hematology medicine.disease Essential hypertension Left ventricular hypertrophy 03 medical and health sciences 0302 clinical medicine Blood pressure Internal medicine Pediatrics Perinatology and Child Health Cardiology Medicine cardiovascular diseases 030212 general & internal medicine Amlodipine Telmisartan business Ventricular remodeling hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Biomedical Research. 29 |
| ISSN: | 0976-1683 |
| DOI: | 10.4066/biomedicalresearch.29-17-3573 |
| Popis: | The aim of this study was to observe the changes in the serum Adiponectin (APN) levels and Left Ventricular Hypertrophy (LVH) in hypertensive patients before and after telmisartan treatment. Two hundred and forty hypertensive patients complicated with LVH were divided into a telmisartan group and an amlodipine group. The changes of these patients’ blood pressure, APN, and Left Ventricular Mass index (LVMI) treatment before and 12 w after treatment were compared. The systolic and diastolic blood pressures in both groups were significantly lower than those before treatment (P 0.05). Serum APN levels in the telmisartan group were significantly higher than those before treatment (P 0.05). Compared with amlodipine, telmisartan significantly increased the serum APN levels and significantly reversed the Left Ventricular Remodeling (LVRM) while reducing the blood pressure. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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