Design of Experiments: Concept and Applications of Plackett Burman Design

Autor:	K. Vanaja, R. H. Shobha Rani
Rok vydání:	2007
Předmět:	Pharmacology Plackett–Burman design Process (engineering) Computer science Design of experiments Screening design Statistics Pharmaceutical Science Multifactor design of experiments software Pharmacology (medical) Industrial engineering
Zdroj:	Clinical Research and Regulatory Affairs. 24:1-23
ISSN:	1532-2521 1060-1333
DOI:	10.1080/10601330701220520
Popis:	Application of statistics has broadened far beyond its origin to various areas of research and one among them is the design of experiments. Design of experiments gathers the maximum amount of information in the lowest number of analyses. In order to optimize a process and maintain repeatability, screening designs are performed. A two-level, mathematically derived multiples of four screening design, popularly known as Plackett-Burman screening design, is thoroughly reviewed in this paper. Application of this design in various areas of research such as formulation development and analytical development has also been focused to explore its potential in screening unbiased estimates of all main effects in the smallest design.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ce67ea95629d5e4d6de5ca6624e0e5bc https://doi.org/10.1080/10601330701220520 Zobrazit plný text záznamu