| Popis: |
Nucleic acid hybridization has been one of the most powerful techniques in molecular biology during the past two decades. The applications of nucleic acid hybridization range from determination of overall similarity between organisms (Brenner, 1989) to determination of even a single base mutation in a given gene. Nucleic acid hybridizations are basically performed in three general ways: (1) solution hybridization, (2) hybridization on membrane filters, and (3) in situ hybridization to cytological preparations. |
