A study into the possible link between anti-epileptic drugs and the risk of fractures in Muckamore Abbey Hospital

Autor:	Carmel Tohill
Rok vydání:	1997
Předmět:	Phenytoin medicine.medical_specialty Pediatrics business.industry Incidence (epidemiology) Liquidised diet Carbamazepine medicine.disease Education Surgery Epilepsy Pharmacotherapy Arts and Humanities (miscellaneous) medicine Vitamin D and neurology business Mobility factor General Psychology medicine.drug
Zdroj:	Journal of Intellectual & Developmental Disability. 22:281-292
ISSN:	1469-9532 1366-8250
DOI:	10.1080/13668259700033501
Popis:	The aims of the study were to investigate whether the effects of anti-epileptic drugs are related to the incidence of fractures; to investigate the role of certain other known factors that may contribute to prevention of fractures; and to advise about methods that may help to prevent the risks of fractures. A list was drawn up of all the patients who had had a fracture in the period 1990 – 1993 inclusive. Their BMI, mobility, diet, sunshine exposure, type of epilepsy (if epileptic), cause of fracture and drug regimen, were recorded. A control group of patients was matched for age, build and epilepsy diagnosis. The liquidised diet used in the hospital was very low in vitamin D and this was rectified by adding margarine instead of butter. The use of phenobarbitone, phenytoin and carbamazepine appeared significant (p=. 03) and also mobility factor (p =. 05). As a result of the survey, an audit is being carried out for diet, times and quantity of sun exposure, types and amount of exercise and monitoring of dr...
Databáze:	OpenAIRE
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