Facile Synthesis of N-Phenyl Benzamidine Derivatives, Their Skin Protecting, and Anti-Aging Activity
| Autor: | Ahmad Raheel, Uzma Ali, Hapipah Mohd Ali, Dina Hajjar, Arwa A. Makki, M. B. Taj, Syed Ahmed Tirmizi, Walla Alelwani, Majid Darroudi |
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| Rok vydání: | 2018 |
| Předmět: |
Free Radical Scavenging Activity
Antioxidant 010405 organic chemistry Chemistry Copper oxide nanoparticles medicine.medical_treatment Elastase General Chemistry 010402 general chemistry 01 natural sciences Benzamidine 0104 chemical sciences Catalysis chemistry.chemical_compound medicine Single crystal Nuclear chemistry |
| Zdroj: | Russian Journal of General Chemistry. 88:2425-2431 |
| ISSN: | 1608-3350 1070-3632 |
| DOI: | 10.1134/s1070363218110270 |
| Popis: | The straight forwarded new green approach to the synthesis of N-phenyl benzamidine derivatives catalyzed by copper oxide nanoparticles (CuOnp) under solvent-free conditions (without microwave radiations and with MW radiation) is presented. All synthesized compounds 3a–3k are characterized by FT-IR, NMR, and single crystal XRD analysis and tested for their antioxidant and elastase inhibition activities. The compounds 3i and 3j demonstrate significant free radical scavenging activity. The accumulated data indicate that some synthesized compounds can be recognized as good anti-aging agents. |
| Databáze: | OpenAIRE |
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