| Autor: |
Hye Jin Jang, Ala Woo, Song Yee Kim, Seung Hyun Yong, Youngmok Park, Kyungsoo Chung, Su Hwan Lee, Ah Young Leem, Sang Hoon Lee, Eun Young Kim, Ji Ye Jung, Young Ae Kang, Young Sam Kim, Moo Suk Park |
| Rok vydání: |
2022 |
| DOI: |
10.21203/rs.3.rs-1923905/v1 |
| Popis: |
Background Systemic sclerosis (SSc) is a heterogeneous autoimmune disease characterized by the dysregulation of fibroblast function, causing multi-organ damage, which often involves the lungs. Combined interstitial lung disease (SSc-ILD) is a major cause of death among patients with SSc. Our study aimed to identify the risk factors for mortality and compare the clinical characteristics of patients with SSc-ILD. Methods Patients were retrospectively enrolled between 2010 and 2018 in a tertiary hospital in Korea. Patients with SSc-ILD were classified into two groups depending on the first pulmonary function test or radiologic findings: extensive (n = 46, forced vital capacity [FVC] 20% disease extent on CT scan) or limited (n = 60, FVC ≥ 70% or |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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