An efficient method for the synthesis of substituted TosMIC precursors

Autor: Peter W. Sheldrake, Neil H. Baine, Mark Mellinger, Joseph Sisko
Rok vydání: 1996
Předmět:
Zdroj: Tetrahedron Letters. 37:8113-8116
ISSN: 0040-4039
DOI: 10.1016/0040-4039(96)01886-2
Popis: Substituted tosylmethyl isocyanides (TosMICs) are useful reagents for which no general method of preparation is available. We describe here a high-yielding method for the synthesis of substituted tosylmethyl formamides, which are readily converted to the corresponding isocyanides.
Databáze: OpenAIRE