Cerebral MR Spectroscopy In Neurologically Asymptomatic Hiv-Infected Patients
| Autor: | B. Kubas, W. Dzienis, A. Wiercińska‐Drapało, D. Prokopowicz, Jerzy Walecki, A. Orzechowska-Bobkiewicz, E. Tarasow |
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| Rok vydání: | 2003 |
| Předmět: |
In vivo magnetic resonance spectroscopy
medicine.medical_specialty Pathology Radiological and Ultrasound Technology business.industry Metabolite AIDS-related complex General Medicine medicine.disease Gastroenterology Asymptomatic Central nervous system disease chemistry.chemical_compound nervous system chemistry Internal medicine Immunopathology medicine Hiv patients Radiology Nuclear Medicine and imaging Asymptomatic HIV medicine.symptom business |
| Zdroj: | Acta Radiologica. 44:206-212 |
| ISSN: | 1600-0455 0284-1851 |
| DOI: | 10.1034/j.1600-0455.2003.00028.x |
| Popis: | Purpose: To detect early metabolic changes in the brain of neurologically asymptomatic HIV-infected patients with normal MR imaging and to find the correlation between 1H MR results and immune status. Material and Methods: Twenty neurologically asymptomatic HIV seropositive patients underwent MR imaging and single-voxel 1H MR spectroscopy (MRS) using a PRESS sequence. For all patients, the signals fromN-acetyl-aspartate (NAA), choline-containing compounds (Cho), creatine-phosphocreatine (Cr) and myoinositol (mI) were compared with 32 healthy volunteers as metabolite ratios and metabolite areas to non-suppressed water area ratios. Results: In HIV patients, the NAA/Cho ratio was significantly lower ( p |
| Databáze: | OpenAIRE |
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