Enantioselective reduction of acetophenone with PMHS and tin(II) complexes of chiral pyridine ligands
| Autor: | Daniele Muroni, Giorgio Chelucci, Ilaria Manca |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
chemistry.chemical_classification
Polymethylhydrosiloxane Ketone Process Chemistry and Technology Enantioselective synthesis chemistry.chemical_element Medicinal chemistry Catalysis chemistry.chemical_compound chemistry Pyridine Organic chemistry Physical and Theoretical Chemistry Tin Trifluoromethanesulfonate Acetophenone |
| Zdroj: | Journal of Molecular Catalysis A: Chemical. 225:11-14 |
| ISSN: | 1381-1169 |
| DOI: | 10.1016/j.molcata.2004.08.017 |
| Popis: | A number of tin(II) complexes, prepared in situ from tin(II) triflate and pyridine derivatives (2,2′:6′,2″-terpyridine, 1,10-phenanthroline, 2,2′-bipyridine, dipyridylmethane, 2-(thiophen-2-yl)pyridine and 2-(2-diphenylphosphinophenyl)-5,6,7,8-tetrahydroquinoline), have been used as chiral catalysts for the reduction of acetophenone in the presence of polymethylhydrosiloxane (PMHS). Yields up to 82% and enantioselectivities up to 19% have been obtained. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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