Differential outcomes in triple negative breast cancer observed among the major ethnic groups in Singapore

Autor: Aric Wei Zheng Lee, Serene Ee Ling Tang, Sherwin Kuah, Ern Yu Tan, Hui Miao, Evan Yu Ze Teo, Patrick Wai Keong Chan, Mikael Hartman
Rok vydání: 2019
Předmět:
Zdroj: Clinical Practice. 16
DOI: 10.37532/fmcp.2019.16(4).1209-1220
Popis: Objectives: Although Triple Negative Breast Cancers (TNBCs) are known as a particularly aggressive subtype, some women have a favorable prognosis and recurrence after the initial few years is uncommon. In this study, we reviewed the outcome of women with TNBC and evaluated factors potentially useful for risk stratification. Methods: Retrospective review was performed of 345 patients diagnosed with TNBC at two local institutes from 2006 to 2011. Detailed analyses focused on 315 women without metastasis. Results: TNBC accounted for 11.3% of cancers diagnosed and was most prevalent among Indian women. Disease recurrence was a significant determinant of overall survival (P
Databáze: OpenAIRE