The Comparative Study of the Frequency of P53 and Ki67 Markers in Ovarian Epithelial Tumors and Their Relationship with Survival in Patients Presenting to Shahid Sadoughi Hospital of Yazd in 2013–2017
| Autor: | Ezatollah Aalipour, Shokouh Taghipour Zahir, Hedeye Nahangi, Mohammad Baghi Yazdi, Koorosh Rahmani |
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| Rok vydání: | 2018 |
| Předmět: |
Oncology
medicine.medical_specialty 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Obstetrics and Gynecology medicine.disease Shahid 03 medical and health sciences Serous fluid 0302 clinical medicine Surgical oncology 030220 oncology & carcinogenesis Statistical significance Internal medicine Biopsy Medicine Immunohistochemistry business Ovarian cancer Mucinous cystadenoma |
| Zdroj: | Indian Journal of Gynecologic Oncology. 16 |
| ISSN: | 2363-8400 2363-8397 |
| DOI: | 10.1007/s40944-018-0202-0 |
| Popis: | Ovarian cancer is the fifth cause of cancer death among women. P53 gene and Ki67 can play a significant role in the progression of tumors. This study was conducted to review the frequency of P53 and Ki67 markers in different types of ovarian epithelial tumors and their relationship with the prognosis of the disease. This descriptive analytical study was done on all paraffin-embedded blocks of patients with ovarian surface epithelial tumors (malignant, benign, and borderline) referred to pathology ward of Shahid Sadoughi educational General Hospital from 2013 to 2017 by using the census method. Ki67 and P53 immunohistochemical tests were then performed on all the samples. Data such as (age, pathology report, survival status, affected side, size of tumor) were extracted from the hospital folders. Data were analyzed in SPSS version 22. P |
| Databáze: | OpenAIRE |
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