| Popis: |
Methods: Data from adult patients diagnosed with PA in 2001-2011, living in the Vastra Gotaland County (in dark blue on the map), were collected from the Swedish Pituitary Registry (SPR). In addition, medical records on all patients diagnosed with PA at the six hospitals in the region were reviewed and patients were included in the SPR if not registered before. Patients with nonfunctioning PA (NFPA) >3 mm and hormone producing PAs (in total n=592 patients) were included in the analyses. Age standardized incidence rates (SIR), given as rate/100000 inhabitants (95% confidence intervals), where calculated using the WHO 2000 standard population as a reference. Conclusions: This is the largest study on the incidence of pituitary adenomas (PAs) from a population of 1.6 million inhabitants. The incidence is 3.9 / 100 000 individuals and year. The study is conducted during times of frequent use of medical imaging and confirms an increased incidence of PAs. The life-time risk of PAs in men is 0.27% and in women 0.29%. |
