Facial Papules in a Child

Autor: Ken Hashimoto, Fiorino M. DiGregorio, Joseph S. Baler
Rok vydání: 1995
Předmět:
Zdroj: Archives of Dermatology. 131:613
ISSN: 0003-987X
DOI: 10.1001/archderm.1995.01690170115020
Popis: REPORT OF A CASE A 19-month-old Albanian girl developed yellow-red papules in both eyelids at age 6 months. Over the past year, new lesions developed on her head and upper trunk. She was asymptomatic and otherwise healthy. The examination revealed multiple scattered 2- to 3-mm yellow-red papules over the scalp and face (Figure 1). A few were present on her upper chest. A complete blood cell count, serum protein electrophoresis, and chemistry panels were normal. Bone marrow aspirate, skeletal survey, chest radiograph, and computed tomographic scan were normal. Histologic findings from a typical lesion are shown (Figure 2). Special stains for CD1 and S100 were positive in a few dermal cells; HLA-DR was strongly positive. Electron microscopy was performed (Figure 3andFigure 4). What is your diagnosis? DIAGNOSIS: Benign cephalic histiocytosis. HISTOPATHOLOGIC FINDINGS The epidermis was slightly atrophic. The dermis contained large histiocytic cells with ground-glass cytoplasm, a few multinucleated giant cells
Databáze: OpenAIRE