Steroid sulphatase activity in trophoblast samples
| Autor: | A. H. Fensom, J. M. Morsman, Kypros H. Nicolaides, S. T. S. Lam, Dulcie V. Coleman, C. H. Rodeck |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Pregnancy Ichthyosis Obstetrics and Gynecology Trophoblast Biology Arylsulphatase C medicine.disease medicine.anatomical_structure Enzyme Endocrinology chemistry Fetal membrane Internal medicine embryonic structures medicine Steroid sulfatase Chorionic villi reproductive and urinary physiology |
| Zdroj: | Journal of Obstetrics and Gynaecology. 5:24-26 |
| ISSN: | 1364-6893 0144-3615 |
| DOI: | 10.3109/01443618409075738 |
| Popis: | SummaryTrophoblast samples were collected transcervically from 16 pregnant women who were undergoing termination of pregnancy at 8 to 13 weeks. Steroid sulphatase and arylsulphatase C activities were assayed on cultured and uncultured chorionic villi, whole fetal membrane homogenate and cultured cells from fetal membrane. High enzyme activities were detected in uncultured chorionic villi, suggesting that it is possible to make the antenatal diagnosis of X-linked ichthyosis by trophoblast sampling. |
| Databáze: | OpenAIRE |
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