A novel entry to xanthones by an intramolecular Diels-Alder reaction involving 2-(1,2-dichlorovinyloxy) aryl dienones

Autor:	Anne E. Fitzgerald, Neelakandha S. Mani, Katerina Otrubova
Rok vydání:	2018
Předmět:	010405 organic chemistry Stereochemistry Aryl Organic Chemistry Aromaticity 010402 general chemistry Ring (chemistry) 01 natural sciences Biochemistry Cycloaddition Pyrone 0104 chemical sciences chemistry.chemical_compound chemistry Intramolecular force Drug Discovery Xanthone Diels–Alder reaction
Zdroj:	Tetrahedron. 74:5715-5724
ISSN:	0040-4020
DOI:	10.1016/j.tet.2018.08.007
Popis:	A wide array of synthetic methods are described in the literature for the preparation of xanthones—a prominent class of tricyclic molecules that occur widely in nature. Majority of these reported methods involve linking the two aromatic rings and forming the central pyrone ring using a variety of classical and non-classical cyclization strategies. In a conceptually different approach, we describe here a new xanthone synthesis wherein both the pyrone and the second aromatic rings were forged in a single step by an intramolecular cycloaddition reaction involving 2-(1,2-dichlorovinyloxy) aryldienones.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cd588c747e7f37566923220e85af37e3 https://doi.org/10.1016/j.tet.2018.08.007 Zobrazit plný text záznamu Full Text from ScienceDirect