Aerobic Copper-Catalyzed Synthesis of (E)-Vinyl Sulfones by Direct C–S Bond Oxidative Coupling

Autor:	Mingteng Xiong, Heping Zhu, Xiao Liang, Yuanjiang Pan, Kexin Shen
Rok vydání:	2019
Předmět:	010405 organic chemistry Chemistry Organic Chemistry Copper catalyzed Oxidative coupling of methane Oxidative phosphorylation 010402 general chemistry 01 natural sciences Medicinal chemistry Coupling reaction 0104 chemical sciences
Zdroj:	The Journal of Organic Chemistry. 84:11210-11218
ISSN:	1520-6904 0022-3263
DOI:	10.1021/acs.joc.9b01400
Popis:	Copper-catalyzed aerobic oxidative C-S bond coupling reaction between thiophenols and aryl-substituted alkenes for (E)-vinyl sulfones synthesis is reported here. With air utilized as a green oxidant, this transformation not only produces various vinyl sulfones in moderate to good yields but also possesses a simple and ecofriendly system. To clarify the mechanism, kinetic experiments has been investigated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cd50a5c25ce31e99282e6e37adaa4a14 https://doi.org/10.1021/acs.joc.9b01400 Zobrazit plný text záznamu