Compaction Force Analysis: Research Tool for Assessing Mass-Produced Acetaminophen Granulations

Autor:	Mark A. Tumbull, J. J. Fitzpatrick, Chris A. Mitchell
Rok vydání:	1997
Předmět:	Pharmacology Development environment Consolidation (soil) business.industry Computer science Organic Chemistry Compaction Pharmaceutical Science Force analysis Pharmaceutical technology Drug Discovery Compressibility Process engineering business
Zdroj:	Drug Development and Industrial Pharmacy. 23:375-378
ISSN:	1520-5762 0363-9045
DOI:	10.3109/03639049709146139
Popis:	The aim of this research is to define a suitable method for comparing the compressibility of acetaminophen granulations. This paper focuses on the derivation of the method and how it will be applied in a large-scale production environment. This new tool will also aid in the analysis of new formulations on a smaller scale in a lab environment. The result is the use of the Leuenberger model for consolidation, which accurately describes the ease of compaction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cd47441aef42dfca812e49c0d567a358 https://doi.org/10.3109/03639049709146139 Zobrazit plný text záznamu