Synthesis of heterocycles on the basis of products of arylation of unsaturated compounds 22.* 3-Aryl-2-chloropropanal in the synthesis of N-Aryl-5-(R-benzyl)-1,3-thiazole-2-amines

Autor:	Roman Voloshchuk, N. D. Obushak, Yu. V. Ostapiuk, Vasyl S. Matiychuk, Nazar I. Pidlypnyi
Rok vydání:	2010
Předmět:	Chemistry Aryl Organic Chemistry Acrolein chemistry.chemical_element Chloride Copper chemistry.chemical_compound Aniline Yield (chemistry) medicine Organic chemistry Thiazole medicine.drug
Zdroj:	Chemistry of Heterocyclic Compounds. 46:495-499
ISSN:	1573-8353 0009-3122
DOI:	10.1007/s10593-010-0537-7
Popis:	3-Aryl-2-chloropropanal was obtained by the reaction of arenediazonium chlorides with acrolein in the presence of copper(II) chloride. N-Aryl(2-pyridyl)-5-(R-benzyl)-1,3-thiazole-2-amines were formed in high yield by the reaction of these aldehydes with aryl- and 2-pyridylthioureas. The same compounds were obtained by the reaction of 5-(R-benzyl)-1,3-thiazole-2-amines with aniline.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cd33fe4e104646523cf0154001567727 https://doi.org/10.1007/s10593-010-0537-7 Zobrazit plný text záznamu Plný text ve formátu PDF