Vitamin D Levels in Full-Term Neonates with Indirect Hyperbilirubinemia
| Autor: | Enas S. Ahmad, Farida F. Negm, Heba A. Mohammed, Neveen Tawfik Abed |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
business.industry
Significant difference Indirect Hyperbilirubinemia Physiology Parathyroid hormone Jaundice 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Vitamin D and neurology medicine Alkaline phosphatase In patient 030212 general & internal medicine medicine.symptom business Full Term |
| Zdroj: | The Egyptian Journal of Hospital Medicine. 81:2030-2035 |
| ISSN: | 2090-7125 |
| Popis: | Background: Jaundice is a common clinical sign in neonatal medicine. Considering the different roles of vitamin D, its lower level may be correlated with neonatal jaundice. Objectives: This study aimed to demonstrate the relationship between serum vitamin D level and neonatal hyperbilirubinemia and to measure its level in their mothers. Subjects and methods: This case-control study was conducted on 90 neonates and their mothers, 60 neonates with hyperbilirubinemia in patients group and 30 healthy neonates age and sex matched in control group . Blood samples from neonates and their mothers were obtained and sent for laboratory estimation of 25-hydroxy vitamin D, calcium, magnesium, phosphorus, alkaline phosphatase and parathyroid hormone. Results: There is highly significant decrease of vitamin D levels among patients than controls, significant negative correlation between vitamin D levels and serum bilirubin in neonates and no significant difference regarding different laboratory parameters among their mothers. Conclusion: Decreased levels of vitamin D were significantly correlated with neonatal indirect hyperbilirubinemia so, low vitamin D can be included among risk factors for neonatal jaundice. |
| Databáze: | OpenAIRE |
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