Spontaneous (Hashimoto-like) chronic lymphocytic thyroiditis in a rhesus macaque (Macaca mulatta)
| Autor: | Gudrun Hintereder, Roland Plesker |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
endocrine system
Pituitary gland Pathology medicine.medical_specialty endocrine system diseases 040301 veterinary sciences medicine.medical_treatment Thyroiditis 0403 veterinary science 03 medical and health sciences Thyroid peroxidase medicine 030304 developmental biology 0303 health sciences biology Thyroid 04 agricultural and veterinary sciences medicine.disease biology.organism_classification Basophilic Rhesus macaque medicine.anatomical_structure biology.protein Animal Science and Zoology Thyroglobulin Lymphocytic Thyroiditis |
| Zdroj: | Primate Biology. 8:37-42 |
| ISSN: | 2363-4715 |
| Popis: | A case of a female, 10-year-old rhesus macaque (Macaca mulatta) with spontaneous chronic lymphocytic thyroiditis is presented. At necropsy, the thyroid gland was slightly enlarged, with up to 2 mm large, round, confluent, beige foci on the surface of both lobes. Histopathologic features resembled human Hashimoto's thyroiditis: multifocally, the interstitium was infiltrated by lymphocytes and variably sized lymphoid follicles. In the pituitary gland, there were increased numbers of large, basophilic cells throughout the adenohypophysis. Using a human electrochemiluminescence immunoassay (ECLIA), no autoantibodies against thyroglobulin, thyroid peroxidase, or thyroid-stimulating hormone receptor were detected. |
| Databáze: | OpenAIRE |
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