| Autor: |
Karl Lauenstein, L.H. Hempelman, Kurt I. Altman, G. L. Haberland |
| Rok vydání: |
1957 |
| Předmět: |
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| Zdroj: |
Biochimica et Biophysica Acta. 26:421-424 |
| ISSN: |
0006-3002 |
| DOI: |
10.1016/0006-3002(57)90025-2 |
| Popis: |
1. 1. Experiments involving the simultaneous in vivo labeling of the glycine and benzoyl moieties of urinary hippuric acid of rats have been described. 2. 2. Urinary hippuric acid labeled in carbon atoms C 7 and C 8 with 14 C contributed by DL -phenylalanine-3- 14 C and glycine-2- 14 C, respectively, was isolated and the specific activity of C 7 and C 8 was determined in an effort to detect changes in the isotope concentrations of the “free” phenylalanine and glycine pools after irradiation with X-rays. 3. 3. The finding of higher specific activity in the benzoyl and glycine moieties of hippuric acid subsequent to X-irradiation is believed to constitute a direct chemical measure of the extent to which breakdown of 14 C-labeled tissue proteins is increased after exposure of rats to X-rays. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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