Probiotic Interventions for Oral Health

Autor: Mette Rose Jørgensen, Svante Twetman
Rok vydání: 2021
Předmět:
Zdroj: Probiotic Research in Therapeutics ISBN: 9789813362352
DOI: 10.1007/978-981-33-6236-9_11
Popis: The evolving understanding that the oral diseases are preventable by modulation of the oral biofilm has paved the way for the use of beneficial bacteria in dentistry. The main oral diseases, dental caries and periodontitis, result from an ecological shift of the health-associated commensal microbiota to a dysbiotic oral biofilm with abundance of acid-tolerating or proteolytic bacteria. In this chapter, we review the current evidence for the role of probiotic bacteria in the prevention and management of oral diseases. There is evidence that probiotic bacteria can prevent early childhood caries when administrated with milk or tablets in daycare settings. For school children and adults, the certainty of evidence is low due to few and small studies with risk of bias. For periodontal diseases, lactobacilli-derived supplements clearly display significant clinical improvements on gingival bleeding and pocket depth when combined with the conventional treatment modalities. Probiotic supplements may also reduce the need of antiseptics and antibiotics in periodontal care. Likewise, probiotics can significantly lower oral Candida counts, ameliorate bad breath and improve oral wound healing. In summary, probiotics play an increasing role in the prevention and comprehensive management of oral diseases, but we need more long-term studies, especially with candidate strains isolated from the oral cavity. In addition to the clinical efficacy, health-economic aspects should be addressed. The development of oral synbiotic products, containing both pre-and probiotics, is of interest for future oral health care.
Databáze: OpenAIRE
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