Prevalence and Antimicrobial Susceptibility of Pyogenic Microorganisms Isolated from Clinical Specimens of Patients of Lower Respiratory Infection

Autor: Mitesh H Patel, Manisha Jain, Gordhan Nakum, Dhara Modi, Nidhi K Sood, Avani M. Patel
Rok vydání: 2012
Předmět:
Zdroj: International Journal of Scientific Research. 2:1-3
ISSN: 2277-8179
Popis: Background :New emerging pathogens and associated antimicrobial resistance mechanisms have been observed in the respiratory tract of patients suffering from pyogenic infection in the last decade. Prevalence rate of metallo-β-lactamase (MBL)-producing Pseudomonas aeruginosa strains, Carbamapenase producing enterobacteriaceae, is growing, apart from prevalent ESBL positive E.coli & Klebsiella pneumoniae. Methods :In this study, 250 respiratory samples (Sputum) of were collected during a 24 months period. Microbiological cultures and antimicrobial susceptibility tests of the most frequently isolated bacteria were performed by standard disk diffusion method as per CLSI guidelines. Results : Out of 250 spu- tum samples, 142 pathogenic bacteria were isolated and characterized. Among the bacteria, Streptococcus pneumonia, Staphy- lococcus aureus (both MSSA & MRSA) & P. aeruginosa (Both MBL producing & Non MBL producing) showed highest prevalence. Conclusions : The detection of MBL-producing P. aeruginosa and MRSA in patients confirms that antimicrobial resistance patterns should be always kept under surveillance. Moreover hygiene regulations in pulmonary clinics should prevent a further spread of resistant bacterial strains.
Databáze: OpenAIRE