Synthesis and Properties of 1,3-Disubstituted Ureas and Their Isosteric Analogs Containing Polycyclic Fragments: I. Synthesis of 1-(Adamantan-1-yl)-3-(fluoro, chlorophenyl)ureas
Autor: | Gennady M. Butov, D. V. Danilov, E. V. Rasskazova, V. V. Burmistrov, V. S. D’yachenko |
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Rok vydání: | 2020 |
Předmět: | |
Zdroj: | Russian Journal of Organic Chemistry. 56:735-740 |
ISSN: | 1608-3393 1070-4280 |
DOI: | 10.1134/s1070428020050024 |
Popis: | A series of 1,3-disubstituted ureas with a phenyl fragment containing fluorine and/or chlorine substituents in different positions were synthesized with yields of 33–80%. 1-Isocyanatoadamantane was prepared for the first time by the reaction of diphenylphosphoryl azide with (adamantan-1-yl)carboxylic acid in a yield of 85%. |
Databáze: | OpenAIRE |
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