Pharmacological activity of echinochrome a alone and in the biologically active additive Timarin

Autor:	N. V. Polyakova, O. N. Krivoshapko, Artyukov Aleksandr A, A. M. Popov, A. V. Tsybulsky
Rok vydání:	2013
Předmět:	Clinical Biochemistry Blood lipids Biological activity Glutathione Biology Pharmacology Biochemistry chemistry.chemical_compound Sex hormone-binding globulin Mechanism of action chemistry Catalase biology.protein medicine Molecular Medicine Echinochrome A medicine.symptom After treatment
Zdroj:	Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 7:237-242
ISSN:	1990-7516 1990-7508
DOI:	10.1134/s1990750813030025
Popis:	Pharmacological activity of echinochrome A (EchA) alone and in the biologically active additives (BAA) Timarin, administered per os has been investigated in volunteers. Blood hematological, immunological, and biochemical parameters were investigated before and after administration of the substances used. EchA decreased serum glutatione (GSH) and increased catalase activity 1 h after treatment. Later (3 h after administration) catalase activity normalized, while GSH exceeded the initial level. Changes in blood lipids suggest decreased risk of atherogenesis. Changes found in blood sex hormone levels indicate that Timarin may influence sex gland functioning. Changes of hematological and immunological parameters have been interpreted as the result of a mild stressor effect of both EchA alone and in the BAA Timarin increasing adaptation reactivity of the body.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cced726644c726fd2db93ad9e49545c4 https://doi.org/10.1134/s1990750813030025 Zobrazit plný text záznamu Full text from SpringerLink