Chlamydia trachomatis detection in adolescents

Autor: Leslie R. Jaffe, Sharon B. Diamond, Angela Diaz, Lorena Siqueira, Neil A. Spielsinger
Rok vydání: 1986
Předmět:
Zdroj: Journal of Adolescent Health Care. 7:401-404
ISSN: 0197-0070
DOI: 10.1016/s0197-0070(86)80242-x
Popis: We compared tissue cell culture isolation with the Microtrak fluorescent monoclonal antibody direct specimen test for detection of endocervical Chlamydia trachomatis in an inner-city population of sexually active Black and Hispanic adolescent girls. Of the 95 patients screened, C. trachomatis was identified in 26.3%. The sensitivity of the direct specimen test was 91.7%, and its specificity was 98.6%. The positive predictive value was 95.6%, and the negative predictive value was 97.2%. No significant difference was found between Blacks (28.6%) and Hispanics (24.1%) in the incidence of endocervical C. trachomatis , nor was the use of an oral contraceptive significantly associated with the diagnosis of C. trachomatis ( p > 0.10). Neisseria gonorrhoeae was isolated in 8.4% of the patients. The direct specimen test appears to be an accurate and convenient method of screening sexually active adolescent girls for genital C. trachomatis . Further study is needed to determine if an oral contraceptive increases the risk of Chlamydia infection in adolescents.
Databáze: OpenAIRE