Characterization of the Positive Transcription Regulator PfaR for Improving Eicosapentaenoic Acid Production in Shewanella putrefaciens W3-18-1

Autor: Hehong Wei, Penghui He, Dianzhen Yu, Shuangyuan Liu, Chengtao Li, Dongru Qiu
Rok vydání: 2023
Předmět:
Zdroj: Applied and Environmental Microbiology. 89
ISSN: 1098-5336
0099-2240
Popis: We have experimentally confirmed that PfaR is a positive transcription regulator that promotes EPA synthesis at low temperature in Shewanella putrefaciens W3-18-1. Overexpression of PfaR in WT strain W3-18-1 could lead to a 1.8-fold increase in EPA productivity at low temperature. It is further shown that PfaR may be regulated by housekeeping Sigma 70 factor at low temperature.
Databáze: OpenAIRE