Characterization of the Positive Transcription Regulator PfaR for Improving Eicosapentaenoic Acid Production in Shewanella putrefaciens W3-18-1
Autor: | Hehong Wei, Penghui He, Dianzhen Yu, Shuangyuan Liu, Chengtao Li, Dongru Qiu |
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Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Applied and Environmental Microbiology. 89 |
ISSN: | 1098-5336 0099-2240 |
Popis: | We have experimentally confirmed that PfaR is a positive transcription regulator that promotes EPA synthesis at low temperature in Shewanella putrefaciens W3-18-1. Overexpression of PfaR in WT strain W3-18-1 could lead to a 1.8-fold increase in EPA productivity at low temperature. It is further shown that PfaR may be regulated by housekeeping Sigma 70 factor at low temperature. |
Databáze: | OpenAIRE |
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