Epidemiology and long term survival of gastric carcinoma in the French district of Finistère between 1984 and 1995
Autor: | Joseph Faycal, Christophe Bessaguet, Jean-Michel Cauvin, Franck Cholet, Jean-Baptiste Nousbaum, Michel Robaszkiewicz, Karine Bideau, Hervé Gouérou |
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Rok vydání: | 2005 |
Předmět: |
medicine.medical_specialty
education.field_of_study Multivariate analysis Linitis plastica Proportional hazards model business.industry Incidence (epidemiology) Population Gastroenterology General Medicine Logistic regression medicine.disease Internal medicine Epidemiology medicine education business Survival rate |
Zdroj: | Gastroentérologie Clinique et Biologique. 29:23-32 |
ISSN: | 0399-8320 |
Popis: | Summary Objectives The aims of this study were to evaluate trends in incidence, clinical characteristics, treatment regimen and prognosis of gastric carcinoma in the area of Finistere (France) during a 12-year period. Methods Between 1984 and 1995, the Finistere Registry of GastroIntestinal Tract Tumors listed 2 139 patients with gastric carcinoma in a population of 838 627 inhabitants. Curative resection and operative mortality were analyzed by logistic regression. Prognostic factors were determined using the Kaplan-Meier method and the Cox model. Results When comparing the second period (1990-1995) to the first period (1984-1989) we observed: a) a decrease of standardized incidence (13.2 vs. 15.6/100 000 inhabitants/year in males and 5.4 vs . 7.0/100 000 inhabitants/year in females); b) a significant increase of linitis plastica (21.4% vs . 10.9%) and infiltrative tumors (53.1 vs. 31.2%) (P vs . 45.0%; P Conclusion This study showed a decrease in the incidence of gastric carcinoma over time and an increase of linitis plasticia and infiltrative forms. Despite improvement in management of patients, the global prognosis of gastric carcinoma did not improve significantly over a 12-year period of observation. |
Databáze: | OpenAIRE |
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