Mixed Surface Chemistry: An Approach to Highly Luminescent Biocompatible Amphiphilic Silicon Nanocrystals
| Autor: | Amran Howlader, Jonathan G. C. Veinot, Muhammad Amirul Islam, Regina Sinelnikov, Angelique Faramus |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Photoluminescence
Bioconjugation Silicon Chemistry Hydrosilylation General Chemical Engineering chemistry.chemical_element Nanoparticle Nanotechnology 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences chemistry.chemical_compound Amphiphile Materials Chemistry 0210 nano-technology Luminescence Biosensor |
| Zdroj: | Chemistry of Materials. 30:8925-8931 |
| ISSN: | 1520-5002 0897-4756 |
| DOI: | 10.1021/acs.chemmater.8b04227 |
| Popis: | Amphiphilic nanoparticles (AP-NPs) are attractive for many far-reaching applications in diverse sectors. Amphiphilic silicon nanocrystals (AP-SiNCs) are particularly promising for luminescence-based bioimaging, biosensing, and drug delivery because of their size- and surface chemistry-dependent photoluminescence (PL), high PL quantum yield, long-term photostability, and robustness to bioconjugation. Numerous studies demonstrated the synthesis of high-quality SiNCs that are compatible with organic solvents. However, preparing water-soluble SiNCs while maintaining their attractive PL properties is very challenging, and to date, only one report of blue-emitting AP-SiNCs has appeared. This report outlines a straightforward one-step thermal hydrosilylation approach that affords AP-SiNCs soluble in aqueous media in high concentrations (i.e., 14.4 mg/mL silicon core-based), exhibit bright long-lived PL in the red/near-infrared spectral region, are biocompatible, and present bioconjugable surface groups. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|