Kidney size is a determinant of structural/functional injury following shock wave treatment of pigs
| Autor: | James E. Lingeman, Anne Trout, Andrew P. Evan, Bret A. Connors, Lynn R. Willis |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
medicine.medical_specialty
Kidney Subcapsular hemorrhage Acoustics and Ultrasonics urogenital system business.industry Urology Renal function Shock wave lithotripsy PAH clearance medicine.anatomical_structure Arts and Humanities (miscellaneous) Renal blood flow Medicine Risk factor business A determinant |
| Zdroj: | The Journal of the Acoustical Society of America. 98:2943-2943 |
| ISSN: | 0001-4966 |
| DOI: | 10.1121/1.414066 |
| Popis: | It has been suggested that kidney size is a risk factor for increased shock wave lithotripsy‐ (SWL) induced damage. This relationship was investigated in pigs of two different ages; ten weeks of age (group 1) and five weeks of age (group 2). Each pig received 2000 shocks, 24 kV to the right kidney. Glomerular filtration rate (GFR), PAH clearance and extraction were measured 1 h before and 1 and 4 h after SWL treatment. The kidneys were harvested at the end of the clearance study. Values for GFR, PAH clearance, and extraction were reduced in the shocked kidney of both groups 1 h post‐SWL. Calculated values for true renal plasma flow showed a greater reduction in the treated kidneys of group 2 versus group 1. The degree of subcapsular hemorrhage and intraparenchymal bleeding and tubular disruption was more extensive in group 2 versus group 1 treated kidneys. The data document the degree of structural and functional injury induced by SWL and support the hypothesis that the effect of SWL is greatest in kidney... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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