A PRC1–RNF2 knockout punch for cancer
| Autor: | Michel DuPage, Janneke G. C. Peeters |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Nature Cancer. 2:996-997 |
| ISSN: | 2662-1347 |
| Popis: | Shedding light on epigenetic mechanisms controlling anti-tumor immune responses, a new study shows that the tumor-intrinsic ring finger protein 2 (RNF2), the catalytic subunit of Polycomb repressor complex 1 (PRC1), acts as a negative regulator of a collaborative NK and CD4+ T cell anti-tumor immune response against breast cancer. |
| Databáze: | OpenAIRE |
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