Structure of the liver as a possible factor in the regulation of ?-fetoprotein synthesis

Autor:	N. I. Khramkova, T. D. Beloshapkina, A. S. Gleiberman
Rok vydání:	1979
Předmět:	medicine.medical_specialty Endocrinology Antigen Regeneration (biology) Internal medicine medicine CCL4 General Medicine Biology General Biochemistry Genetics and Molecular Biology Membrane antigen
Zdroj:	Bulletin of Experimental Biology and Medicine. 87:607-610
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00801399
Popis:	During regeneration of the mouse liver after poisoning with CCl4 and paracetamol, hepatocytes containing α-fetoprotein (αFP) lose their membrane antigen that served as marker for biliary capilaries. Both during regeneration and in early postnatal development, cessation of αFP synthesis by the cells coincides with the appearance of an antigen marking the biliary capillaries on their surface. It is suggested that cessation of αFP synthesis is the result of establishment of a system of contacts characteristic of the definitive hepatic column.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ccb4410101be0f8358a9123d85b4029b https://doi.org/10.1007/bf00801399 Zobrazit plný text záznamu Full text from SpringerLink