Adjudicated myocarditis and multisystem illness trajectory in healthcare workers post-COVID-19

Autor: Robert Sykes, Andrew J Morrow, Alex McConnachie, Anna Kamdar, C Bagot, Hannah Bayes, Kevin G Blyth, Michael Briscoe, Heeraj Bulluck, David Carrick, Colin Church, David Corcoran, C Delles, Iain Findlay, Vivienne B Gibson, Lynsey Gillespie, Douglas Grieve, Pauline Hall Barrientos, Antonia Ho, N N Lang, David J Lowe, Vera Lennie, Peter MacFarlane, Kaithlin J Mayne, Patrick Mark, Alasdair McIntosh, Ross McGeoch, Christopher McGinley, Connor Mckee, Sabrina Nordin, Alexander Payne, Alastair Rankin, Keith E Robertson, Nicola Ryan, Giles H Roditi, Naveed Sattar, David B Stobo, Sarah Allwood-Spiers, Rhian Touyz, Gruschen Veldtman, Sarah Weeden, Stuart Watkins, Paul Welsh, Ryan Wereski, Kenneth Mangion, Colin Berry
Rok vydání: 2023
Předmět:
Zdroj: Open Heart. 10:e002192
ISSN: 2053-3624
DOI: 10.1136/openhrt-2022-002192
Popis: BackgroundWe investigated the associations of healthcare worker status with multisystem illness trajectory in hospitalised post-COVID-19 individuals.Methods and resultsOne hundred and sixty-eight patients were evaluated 28–60 days after the last episode of hospital care. Thirty-six (21%) were healthcare workers. Compared with non-healthcare workers, healthcare workers were of similar age (51.3 (8.7) years vs 55.0 (12.4) years; p=0.09) more often women (26 (72%) vs 48 (38%); pIn adjusted multivariate logistic regression analysis, healthcare worker status associated with a binary classification (probable/very likely vs not present/unlikely) of adjudicated myocarditis (OR: 2.99; 95% CI (1.01 to 8.89) by 28–60 days postdischarge).After a mean (SD, range) duration of follow-up after hospital discharge of 450 (88) days (range 290, 627 days), fewer healthcare workers died or were rehospitalised (1 (3%) vs 22 (17%); p=0.038) and secondary care referrals for post-COVID-19 syndrome were common (42%) and similar to non-healthcare workers (38%; p=0.934).ConclusionHealthcare worker status was independently associated with the likelihood of adjudicated myocarditis, despite better antecedent health. Two in five healthcare workers had a secondary care referral for post-COVID-19 syndrome.Trial registration numberNCT04403607.
Databáze: OpenAIRE