Structures of the major human metabolites of docetaxel (RP 56976 - Taxotere®)

Autor:	Marc Vuilhorgne, B. Monegier, S. Sablé, C. Gaillard
Rok vydání:	1994
Předmět:	Human feces Chromatography Chemistry Metabolite Organic Chemistry Biochemistry High-performance liquid chromatography Biological materials chemistry.chemical_compound Docetaxel Drug Discovery medicine Side chain oxidation Feces medicine.drug
Zdroj:	Tetrahedron Letters. 35:3715-3718
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)73079-6
Popis:	The structures of the main human metabolites of docetaxel (RP 56976-Taxotere®) isolated from human feces have been established using HPLC/MS-MS and 600 MHz NMR experiments. These metabolites are C-13 side chain oxidation derivatives of the parent compound.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cc817670863b3292f0f4bbbd1cdd44b2 https://doi.org/10.1016/s0040-4039(00)73079-6 Zobrazit plný text záznamu