An assessment of antituberculosis therapy in two animal models
| Autor: | Adolfo Turano, Giuseppe Sacchi, Raul Pizzi, L. Peroni, G. Ravizzola |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Tuberculosis
medicine.drug_class Rufloxacin Antibiotics General Medicine Biology bacterial infections and mycoses medicine.disease biology.organism_classification Applied Microbiology and Biotechnology Microbiology Guinea pig Mycobacterium tuberculosis Ciprofloxacin chemistry.chemical_compound chemistry Immunology medicine Rifampicin Antibacterial agent medicine.drug |
| Zdroj: | Current Microbiology. 29:237-240 |
| ISSN: | 1432-0991 0343-8651 |
| DOI: | 10.1007/bf01570160 |
| Popis: | The protective effects of ciprofloxacin and rufloxacin were compared to those of rifampicin againstMycobacterium tuberculosis infections in mice and in guinea pigs. Rifampicin was very protective in both models. In tubercular infections produced in mice, ciprofloxacin (30 mg/kg) showed slight protection but none was observed in guinea pigs. Rufloxacin, was weakly active in guinea pigs but inactive in mice. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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