Novel Wire Planning Schemes for Pin Minimization in Digital Microfluidic Biochips
Autor: | Parthasarathi Dasgupta, Hafizur Rahaman, Pranab Roy, Swati Saha |
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Rok vydání: | 2016 |
Předmět: |
010302 applied physics
Engineering Interconnection business.industry Suite Microfluidics 02 engineering and technology 01 natural sciences 020202 computer hardware & architecture Hardware and Architecture 0103 physical sciences Hardware_INTEGRATEDCIRCUITS 0202 electrical engineering electronic engineering information engineering Benchmark (computing) Electronic engineering Algorithm design Minification Electrical and Electronic Engineering Routing (electronic design automation) business Biochip Software Computer hardware |
Zdroj: | IEEE Transactions on Very Large Scale Integration (VLSI) Systems. 24:3345-3358 |
ISSN: | 1557-9999 1063-8210 |
DOI: | 10.1109/tvlsi.2016.2541671 |
Popis: | Digital microfluidic biochips (DMFBs), a second-generation lab-on-chip device has developed in recent years as a feasible alternative to conventional laboratory procedure for biochemical analysis and diagnostic applications. These devices enable the precise manipulation of nanoliter volumes of biological fluids and chemical reagents within a 2-D rectangular array of electrodes. Increasing number of control pin requirements together with high wire planning complexity becomes a major issue for integrated execution of multiple bioassays within a single DMFB layout. In this paper, we propose new techniques for interconnection wire routing for actuating the electrodes operating at identical time sequence. Here, we propose three different algorithms to develop feasible wire plans for a given layout with an aim to minimize the overall number of control pin count. Multiple actuation on the same pin termed multiphasing is proposed to resolve the issue of wire planning for handling the issue of cross contamination at any particular site. The proposed techniques are implemented in layouts using testbenches for benchmark suite III and selective testbenches for benchmark suite I. The results obtained through simulation show encouraging improvement over contemporary contributions. |
Databáze: | OpenAIRE |
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